pentobarbital will lower the level or outcome of larotrectinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism.pentobarbital will minimize the level or influence of doxorubicin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.Contraindicated (1)pentobarbital decreases amounts of vandetanib by affecting hepati